Integration of Genomics and Bioinformatics for Personalized Medicine: Predicting Drug Responses and Optimizing Treatment Plans

Authors

  • Shankar Lal Public Health School, Tharparkar, Pakistan.
  • Saeed Ahmed Liaquat University of Medical & Health Sciences, Jamshoro, Pakistan.
  • Tabeel Tariq Bashir Lincoln University College - Kota Bharu Jalan Lembah Sireh, 15050 Kota Bharu, Kelantan, Malaysia.
  • Avesh Kumar Liaquat University of Medical & Health Sciences, Jamshoro, Pakistan.
  • Muhammad Furquan Liaquat University of Medical & Health Sciences, Jamshoro, Pakistan.

Keywords:

Personalized Medicine, Genomics, Bioinformatics, Drug Response Prediction, Machine Learning in EEG, Pharmacogenomics

Abstract

The integration of genomics and bioinformatics has revolutionized individualized medicine by enabling precise prediction of medicine responses and optimization of personalized treatment plans. This paper reviews current methodologies in genomic data accession, bioinformatics channels and multi omics data integration to identify clinically practicable biomarkers. We discuss machine literacy models that work high- dimensional genomic and clinical data to prognosticate remedial efficacy and adverse medicine responses with high accuracy. Clinical operations across oncology, psychiatry and cardiovascular drug demonstrate significant advancements in patient issues when treatment opinions are guided by genomic perceptivity. Also, we address critical ethical, legal and social counteraccusations, emphasizing the significance of data privacy, informed concurrence and indifferent access to genomic technologies. Challenges similar as data diversity, limited population diversity and clinical implementation walls are anatomized, alongside unborn directions including real- world data integration, advanced single- cell genomics and AI interpretability. This comprehensive approach underscores the transformative eventuality of genomics and bioinformatics in advancing substantiated healthcare and perfecting treatment efficacy while promoting responsible and indifferent use.

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Published

2025-06-01

How to Cite

Shankar Lal, Saeed Ahmed, Tabeel Tariq Bashir, Avesh Kumar, & Muhammad Furquan. (2025). Integration of Genomics and Bioinformatics for Personalized Medicine: Predicting Drug Responses and Optimizing Treatment Plans. Journal of Computing & Biomedical Informatics, 9(01). Retrieved from https://jcbi.org/index.php/Main/article/view/990